Immune
Benefits of Breastfeeding at a Glance
White Blood Cells
- B lymphocytes
- Give rise to antibodies targeted against specific microbes
- Macrophages
- Kill microbes outright in the baby's gut, produce lysozymes and activate
other components of the immune system
- Neutrophils
- May act as phagocytes, ingesting bacteria in the baby's digestive system
- T lymphocytes
- Kill infected cells directly or send out chemical messages to mobilize
other defences. They proliferate in the presence of organisms that cause
serious illness in infants. They also manufacture compounds that can
strengthen a child's own immune system.
Molecules
- Antibodies of secretory IgA class
- Bind to microbes in the baby's digestive tract and thereby prevent them
from passing through walls of the gut into the body's tissues
- B12 binding protein
- Reduces amount of vitamin B12, which bacteria need in order to grow
- Bifidus factor
- Promotes growth of Lactobacillus bifidus, a harmless bacterium, in
baby's gut. Growth of such nonpathogenic bacteria helps to crowd out dangerous
varieties
- Fatty acids
- Disrupt membranes surrounding certain viruses and destroy them
- Fibronectin
- Increases antimicrobial activity of macrophages; helps to repair tissues
that have been damaged by immune reaction inthe baby's gut.
- Gamma-interferon
- Enhances antimicrobial activity of the immune cells
- Hormones and growth factors
- Stimulate the baby's digestive tract to mature more quickly. Once the
initial "leaky" membranes lining the gut mature, infant become less vulnerable
to microorganisms.
- Lactoferrin
- Binds to iron, a mineral many bacteria need to survive. By reducing the
available amount of iron, lactoferrin thwarts growth of pathogenic bacteria
- Lysozyme
- Kills bacteria by disrupting their cell walls
- Mucins
- Adhere to bacteria and viruses, thus keeping such microorganisms from
attaching to mucosal surfaces
- Oligosaccharides
- Bind to microorganisms and bar them from attaching to mucosal surfaces
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